Natural Product Chemistry Lab

The emphasis in this lab course will be on isolation and identification methods. Students will be introduced to various chromatographic techniques, from manual to automated, which they will apply to separation of particular natural products out of a crude mixture. Experiments using different methods such as normal/reversed phase, size exclusion, will enable students to select the best route for any specific purpose. During the second half of the course each student will be assigned to a mini-project. Where students will be expected to learn how to use advanced instruments, such LC-MS, and evaluate the data for structure determination purposes. Prerequisite: CH 362/CH 362L. Materials intensive fee applies. Concurrent registration in CH 440 required.