Natural Product Chemistry

The vast number of naturally occurring substances will be classified in terms of the biosynthetic-biogenetic pathways of their productions. Polyketides, terpenes, alkaloids, as well as compounds with other and mixed biogenetic origins will be studies using mechanistic predictions introduced at the beginning of the course rather than a traditional descriptive approach. Secondary metabolites that are not emphasized in biochemistry courses will be highlighted with a view to understand their ecological significance, particularly in the field of chemical communication. Some interesting novel molecules isolated from marine organisms will be discussed. Prerequisite: CH 362/CH 362L. Concurrent registration in CH 440L recommended not required.